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[实验性酒精中毒时皮质神经元变化的可逆性]

[Reversibility of the changes in cortical neurons in experimental alcoholic intoxication].

作者信息

Popova E N

出版信息

Biull Eksp Biol Med. 1983 Aug;96(8):101-4.

PMID:6683977
Abstract

The structure of neurons and dendrites in the sensorimotor cortex of rats was studied at varying times after completion of a 2-month alcoholic intoxication. The pathological process in the cortex was found to be under way at the early time after alcohol withdrawal. The signs of the recovery of the intracellular organization in neurons and dendrites were noticed 40 days after alcohol withdrawal. However, regardless of the fact that the structure of the most preserved neurons gets recovered 2 months after alcohol withdrawal, the structural organization of dendrites does not attain complete recovery.

摘要

在大鼠完成2个月酒精中毒后的不同时间,对其感觉运动皮层中的神经元和树突结构进行了研究。发现酒精戒断后的早期,皮层中的病理过程就已开始。酒精戒断40天后,观察到神经元和树突中细胞内组织恢复的迹象。然而,尽管大多数保存下来的神经元结构在酒精戒断2个月后得以恢复,但树突的结构组织并未完全恢复。

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