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[一种用于客观测量和量化局部抗炎药物效果的新模型]

[A new model for objective measurement and quantification of the effects of topical anti-inflammatory agents].

作者信息

Albrecht H, Lücker P W, Venitz J

出版信息

Arzneimittelforschung. 1983;33(6):900-1.

PMID:6684448
Abstract

A new model is presented with aid of which the antiinflammatory effect of topically administered substances can be measured. The basic measuring device is a reflex densitometer with mobile measuring head that can determine the redness of the tesa-film stripped skin directly without photographical intermediaries. The relevance of the model is demonstrated by the healing curve exhibited by the stripped skin which has been treated with a fluprednylidene acetate containing cream.

摘要

提出了一种新模型,借助该模型可以测量局部给药物质的抗炎效果。基本测量装置是一台带有可移动测量头的反射密度计,它可以直接测定去除tesa膜的皮肤的发红情况,无需摄影中介。用含醋酸氟泼尼定的乳膏治疗后的去皮皮肤呈现的愈合曲线证明了该模型的相关性。

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