Romero A, Grau T, Sacristán A, Ortiz J A
Arzneimittelforschung. 1983;33(7A):1035-8.
Two groups of rats were administered by oral route doses of 100 and 150 mg/kg, respectively, of cytidine diphosphate choline (CDP-choline citicoline, Somazina), daily during 30 days. At the end of the test, animals were killed and necropsied, evaluating the urinary, haematological, serum biochemistry and histopathological parameters. The study did not reveal any signs of toxicity.
将两组大鼠分别通过口服途径给予胞二磷胆碱（胞磷胆碱，索马嗪），剂量分别为100毫克/千克和150毫克/千克，持续30天，每日给药。试验结束时，处死动物并进行尸检，评估尿液、血液学、血清生物化学和组织病理学参数。该研究未发现任何毒性迹象。
