利用连锁DNA多态性对杜氏肌营养不良症家系进行基因型预测。
The use of linked DNA polymorphisms for genotype prediction in families with Duchenne muscular dystrophy.
作者信息
Harper P S, O'Brien T, Murray J M, Davies K E, Pearson P, Williamson R
出版信息
J Med Genet. 1983 Aug;20(4):252-4. doi: 10.1136/jmg.20.4.252.
Abstract
Two DNA restriction fragment length polymorphisms show genetic linkage to the Duchenne muscular dystrophy locus on the short arm of the X chromosome. Examples are given of families in which these polymorphisms can be used in the prediction of genotype for this disorder.
摘要
两种DNA限制性片段长度多态性显示出与X染色体短臂上的杜兴氏肌营养不良基因座存在遗传连锁关系。文中给出了一些家族的例子，其中这些多态性可用于预测该疾病的基因型。
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本文引用的文献
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