Romero-Ayala L C, Vera A, Zavaleta D, Casanova J M, Buendía A, Ovseyevitz J, Cárdenas M, Attie F
Arch Inst Cardiol Mex. 1983 May-Jun;53(3):217-22.
Fifty eight patients with isolated with discrete subaortic stenosis or in association with just another heart defect, were studied between 1961 and 1980. The age range was between 2 and 42 years. The evaluation of each case was done according to clinical manifestations, systolic overloading of the left ventricle and the amount of the systolic gradient. There is a poor correlation between the clinical, electrocardiographic and hemodynamic parameters according to the student t test in the preoperative evaluation. Forty-one patients were operated, two of them died in the early post-operative period. There was a good clinical evolution with significant values comparing pre and post-operative symptoms. The decrease in the systolic gradient in 26 cases after surgery was significative (p less than or equal to 0.005). Based on the natural history of this malformation and on the results obtained with the surgical treatment, we may conclude that there is surgical indication once the diagnosis is made, because this malformation has a completely different evolution compared with other forms of congenital aortic stenosis.
1961至1980年间，对58例孤立性离散性主动脉瓣下狭窄或合并其他心脏缺陷的患者进行了研究。这些患者的年龄在2至42岁之间。根据临床表现、左心室收缩期负荷过重情况以及收缩期压力阶差对每例病例进行评估。术前评估中，根据学生t检验，临床、心电图和血流动力学参数之间存在较差的相关性。41例患者接受了手术，其中2例在术后早期死亡。与术前症状相比，术后症状有显著改善，临床进展良好。26例患者术后收缩期压力阶差下降显著（p小于或等于0.005）。基于这种畸形的自然病史以及手术治疗所取得的结果，我们可以得出结论，一旦确诊，就有手术指征，因为这种畸形与其他形式的先天性主动脉狭窄相比，其病情发展完全不同。
