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[一例分泌催乳素的微腺瘤导致青春期男孩溢乳及青春期延迟]

[A prolactin-producing microadenoma as the cause of galactorrhea and delayed puberty in an adolescent boy].

作者信息

Böhles H, Fahlbusch R, Becker H, Schill W B, Stehr K

出版信息

Monatsschr Kinderheilkd. 1983 Oct;131(10):736-9.

PMID:6685820
Abstract

The case history of a 16 years old boy with delayed puberty and the sudden onset of galactorrhea is presented. Prolactin analyses and X-ray studies of the sella turcica lead to the diagnosis of a pituitary tumor. A prolactin producing microadenoma was selectively excised via the transsphenoidal route. Serum prolactin resumed normal concentrations within hours after the operation. During the next months the boy showed the signs of normal puberty with increasing concentrations of serum testosterone. Because serum prolactin concentrations remained within the normal range, therapy with bromocriptine was not necessary. A spermiogram however, performed seven months after the operation, showed signs of a viscosipathy and terato-asthenozoospermia.

摘要

本文介绍了一名16岁青春期延迟且突然出现溢乳症状男孩的病例史。通过催乳素分析和蝶鞍的X线检查确诊为垂体瘤。经蝶窦途径选择性切除了分泌催乳素的微腺瘤。术后数小时内血清催乳素恢复至正常浓度。在接下来的几个月里,男孩出现了正常青春期的体征,血清睾酮浓度不断升高。由于血清催乳素浓度一直保持在正常范围内,因此无需使用溴隐亭治疗。然而,术后七个月进行的精液分析显示有精液黏稠病和畸形弱精子症的迹象。

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