Shimizu K, Maekawa K
Acta Anat (Basel). 1983;117(3):257-60. doi: 10.1159/000145795.
This study was undertaken to determine where most of the uterine collagen is degraded during the postpartum involution. The greater part of uterine collagen, which was estimated as hydroxyproline, had disappeared by day 2 post partum. Colchicine, which decreases phagocytic activity, did not affect the uterine collagen degradation. Phagocytic activity in the post partum uterus did not appear until day 3 post partum. These results suggest that most of the uterine collagen is degraded by the extracellular but not by the intracellular pathway.
本研究旨在确定产后子宫复旧过程中大部分子宫胶原蛋白在何处降解。以羟脯氨酸估算的子宫胶原蛋白大部分在产后第2天就已消失。秋水仙碱可降低吞噬活性，但不影响子宫胶原蛋白的降解。产后子宫的吞噬活性直到产后第3天才出现。这些结果表明，大部分子宫胶原蛋白是通过细胞外途径而非细胞内途径降解的。
