Chalifoux A, Dallaire A
Am J Vet Res. 1983 Dec;44(12):2412-7.
Pure CO was used to euthanatize 18 dogs. During the procedure, physiologic parameters: EEG, ECG, arterial blood pressure, heart rate, respiratory rate, and cortisol values were monitored. Behavioral manifestations were also noted. The EEG modifications indicated a cortical voltage increase followed by rapid cerebral death. Higher heart and respiratory rates during EEG modifications indicated stress, and arterial blood pressure decreased significantly (P = less than 0.05) at the same time. Serum cortisol values were already high before the euthanasia process. Based on these observations, a precise time could not be set for unconsciousness. A gray zone, during which vocalization and agitation occurred for approximately 20 to 25 s, was 3 to 8 s in 10 dogs. These behavioral manifestations could still occur in the conscious phase.
使用纯一氧化碳对18只狗实施安乐死。在该过程中，监测了生理参数：脑电图（EEG）、心电图（ECG）、动脉血压、心率、呼吸频率和皮质醇值。还记录了行为表现。脑电图的变化表明皮质电压升高，随后迅速出现脑死亡。脑电图变化期间较高的心率和呼吸频率表明存在应激反应，同时动脉血压显著下降（P<0.05）。血清皮质醇值在安乐死过程开始前就已经很高。基于这些观察结果，无法确定意识丧失的确切时间。10只狗中有3至8秒出现了一个灰色区域，在此期间会发声和躁动约20至25秒。这些行为表现仍可能发生在清醒阶段。
