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一项针对精神障碍个体中痕量胺分解代谢的研究,特别关注伴有惊恐发作的广场恐惧症患者。

A study of the catabolism of trace amines in mentally disordered individuals with particular reference to agoraphobic patients with panic attacks.

作者信息

Yu P H, Bowen R C, Davis B A, Boulton A A

出版信息

Prog Neuropsychopharmacol Biol Psychiatry. 1983;7(4-6):611-5. doi: 10.1016/0278-5846(83)90033-7.

DOI:10.1016/0278-5846(83)90033-7
PMID:6686698
Abstract

Platelet MAO activity toward several trace amine substrates and the plasma levels of some trace acids have been investigated. Compared to controls, the agoraphobic patients were found to have significantly increased MAO activity. The substrate specificity in some of the patients appeared to be altered. The plasma levels of p-HPA and m-HPA were significantly lower than those of the control groups.

摘要

已经研究了血小板单胺氧化酶(MAO)对几种痕量胺底物的活性以及一些痕量酸的血浆水平。与对照组相比,发现广场恐惧症患者的MAO活性显著增加。部分患者的底物特异性似乎发生了改变。对羟基苯乙酸(p-HPA)和间羟基苯乙酸(m-HPA)的血浆水平显著低于对照组。

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A study of the catabolism of trace amines in mentally disordered individuals with particular reference to agoraphobic patients with panic attacks.一项针对精神障碍个体中痕量胺分解代谢的研究,特别关注伴有惊恐发作的广场恐惧症患者。
Prog Neuropsychopharmacol Biol Psychiatry. 1983;7(4-6):611-5. doi: 10.1016/0278-5846(83)90033-7.
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Acta Psychiatr Scand. 1983 Mar;67(3):188-94. doi: 10.1111/j.1600-0447.1983.tb00340.x.
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