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膳食补充硬脂酸对心肌损伤严重程度的影响。

Effect of dietary supplementation with stearic acid on the severity of myocardial lesions.

作者信息

Clandinin M T, Yamashiro S

出版信息

Res Vet Sci. 1983 Nov;35(3):306-9.

PMID:6686716
Abstract

Histological studies were conducted on ventricular myocardium obtained from male rats of the Sprague-Dawley strain after 16 weeks of feeding diets containing 20 per cent (w/w) soybean oil, low erucic acid rapeseed oil or high erucic acid rapeseed oil. Additional groups of rats were fed similar diets supplemented with up to 8 g/kg of tristearin. Increasing dietary intake of stearic acid normalised the plasma ratio of C16:0 to C18:0 for rapeseed oil treatments to ratios analogous to that observed for rats fed soybean oil. Tristearin supplementation did not have a significant effect on myocardial lesion incidence but decreased the severity of lesions observed for rapeseed oil treatments.

摘要

对16周来一直食用含20%(重量/重量)大豆油、低芥酸菜籽油或高芥酸菜籽油饮食的斯普拉格-道利品系雄性大鼠的心室心肌进行了组织学研究。另外几组大鼠食用添加了高达8克/千克硬脂酸甘油酯的类似饮食。增加饮食中硬脂酸的摄入量,可使菜籽油处理组的血浆C16:0与C18:0比例恢复正常,达到与食用大豆油的大鼠所观察到的比例相似。添加硬脂酸甘油酯对心肌损伤发生率没有显著影响,但降低了菜籽油处理组所观察到的损伤严重程度。

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1
Effect of dietary supplementation with stearic acid on the severity of myocardial lesions.膳食补充硬脂酸对心肌损伤严重程度的影响。
Res Vet Sci. 1983 Nov;35(3):306-9.
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引用本文的文献

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Lipids. 2000 Jun;35(6):607-12. doi: 10.1007/s11745-000-0563-5.
2
Cardiac lipid changes in rats fed oils enriched in saturates and their apparent relationship to focal heart lesions.喂食富含饱和脂肪酸油脂的大鼠心脏脂质变化及其与局灶性心脏病变的明显关系。
Lipids. 1985 Oct;20(10):635-44. doi: 10.1007/BF02534381.
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Myocardial diseases of animals.动物的心肌疾病
Am J Pathol. 1986 Jul;124(1):98-178.
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Effects of dietary saturated fat on erucic acid induced myocardial lipidosis in rats.膳食饱和脂肪对芥酸诱导的大鼠心肌脂质osis的影响。
Lipids. 1992 Aug;27(8):619-23. doi: 10.1007/BF02536120.