Whitworth N S, Morrison J C, Whitton A C, Bowers K K
Am J Obstet Gynecol. 1983 Mar 15;145(6):752-6. doi: 10.1016/0002-9378(83)90586-0.
Surfactant foam test scores were quantified by measuring the percent ring (%R) of foam produced at the meniscus of the 1:1 dilution tube. A comparison of %R scoring with conventional negative-positive rating of the foam test indicated that the %R value provided a more accurate estimate of the lecithin/sphingomyelin ratio. Based on clinical assessment of the newborn infant, the %R score also reduced the incidence of false negative test results by 47%. Variations in the assay ethanol fraction or tube size, as well as low amniotic fluid lecithin concentrations, were found to be potential determinants of false negative foam test results. The incidence of these false negative findings can be reduced by use of a %R score that has been empirically calibrated against neonatal outcome.
通过测量1:1稀释管弯月面处产生的泡沫的百分环（%R）对表面活性剂泡沫试验分数进行量化。将%R评分与泡沫试验的传统阴性-阳性评级进行比较表明，%R值能更准确地估计卵磷脂/鞘磷脂比值。基于对新生儿的临床评估，%R评分还将假阴性试验结果的发生率降低了47%。发现测定乙醇分数或试管大小的变化以及羊水卵磷脂浓度低是假阴性泡沫试验结果的潜在决定因素。使用根据新生儿结局经经验校准的%R评分可降低这些假阴性结果的发生率。
