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Delta-sleep-inducing peptide (DSIP) as a factor facilitating animals' resistance to acute emotional stress.

作者信息

Sudakov K V, Ivanov V T, Koplik E V, Vedjaev D F, Michaleva I I, Sargsjan A S

出版信息

Pavlov J Biol Sci. 1983 Jan-Mar;18(1):1-5. doi: 10.1007/BF03004904.

DOI:10.1007/BF03004904
PMID:6687936
Abstract

Delta-sleep-inducing peptide (DSIP) effects on resistance to acute emotional stress induced by electric stimulation of the ventromedial hypothalamus and skin of immobilized rats have been investigated. On the basis of the pattern of cardiovascular reactions, three groups of rats were distinguished: resistant, adapted, and predisposed to the experimental emotional stress. It is shown that DSIP injections increase animals' resistance to acute emotional stress. DSIP also changes the vascular reactivity to episodic emotiogenic stimulations. It is revealed that, after DSIP application, the absence of vascular reactions to emotiogenic ventromedial hypothalamic and electro-skin stimulations significantly increased.

摘要

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The effect of delta-sleep-inducing peptide on the lifespan and incidence of spontaneous tumors in mice.

本文引用的文献

1
Delta sleep-inducing peptide (DSIP): EEG and motor activity in rabbits following intravenous administration.δ睡眠诱导肽（DSIP）：静脉注射后家兔的脑电图和运动活动
Neurosci Lett. 1977 Oct;6(1):9-13. doi: 10.1016/0304-3940(77)90057-x.
2
[Dynamics of individual cardiovascular reactions in rabbits during acute experimental emotional stress].[急性实验性情绪应激期间家兔个体心血管反应的动态变化]
Biull Eksp Biol Med. 1980 Jun;89(6):662-4.
3
The delta-sleep inducing peptide (DSIP) increases duration of sleep in rats.
δ-睡眠诱导肽对小鼠寿命和自发性肿瘤发生率的影响。
Dokl Biol Sci. 2003 Jan-Feb;388:28-30. doi: 10.1023/a:1022487624627.
4
Regulation by delta-sleep-inducing peptide of the neurochemical changes in the brain associated with dopaminergic system hyperactivity.
Neurochem Res. 1999 Sep;24(9):1135-41. doi: 10.1023/a:1020760303553.
5
The influence of the delta-sleep-inducing peptide on convulsive activity.δ-睡眠诱导肽对惊厥活动的影响。
Neurosci Behav Physiol. 1993 Sep-Oct;23(5):480-5. doi: 10.1007/BF01183011.
6
Comparison of DSIP- (delta sleep-inducing peptide) and P-DSIP-like (phosphorylated) immunoreactivity in cerebrospinal fluid of patients with senile dementia of Alzheimer type, multi-infarct syndrome, communicating hydrocephalus and Parkinson's disease.阿尔茨海默型老年痴呆症、多发性梗死综合征、交通性脑积水及帕金森病患者脑脊液中促睡眠肽（DSIP，δ睡眠诱导肽）和类磷酸化促睡眠肽（P-DSIP）免疫反应性的比较
J Neurol. 1987 Oct;235(1):16-21. doi: 10.1007/BF00314191.
7
Delta sleep-inducing peptide as a factor increasing the content of substance P in the hypothalamus and the resistance of rats to emotional stress.δ睡眠诱导肽作为一种增加大鼠下丘脑P物质含量及增强其对情绪应激抵抗力的因子。
Neurosci Behav Physiol. 1992 Jul-Aug;22(4):275-9. doi: 10.1007/BF01182865.
Neurosci Lett. 1979 Jul;13(2):169-72. doi: 10.1016/0304-3940(79)90036-3.
4
[Effects of the oligopeptide sleep neuromodulator in rats, rabbits and dogs].[寡肽睡眠神经调节剂对大鼠、兔和犬的影响]
Zh Evol Biokhim Fiziol. 1979 Jul-Aug;15(4):379-84.