Colpaert F C, Niemegeers C J, Janssen P A
J Pharm Pharmacol. 1976 Mar;28(3):183-7. doi: 10.1111/j.2042-7158.1976.tb04127.x.
The ability of drugs to produce the narcotic discriminative stimulus complex is found to be highly correlated with their analgesic activity; in contrast, no relation with their antidiarrhoeal activity is evident. The findings suggest that the narcotic discriminative stimulus complex is a centrally mediated effect of narcotic drugs.
已发现药物产生麻醉性辨别刺激复合体的能力与其镇痛活性高度相关;相比之下,与它们的止泻活性则无明显关系。这些发现表明,麻醉性辨别刺激复合体是麻醉药物的一种中枢介导效应。