Acar J, Michel P L, Chomette G, Iung B, Starkman C
Hôpital Tenon, service de cardiologie, Paris.
Arch Mal Coeur Vaiss. 1991 Jan;84(1):105-11.
Although dystrophic aortic regurgitation is considered to be a rare condition, if aortic regurgitation due to cystic media-necrosis which usually presents with annulo-aortic ectasia and regurgitation due to dystrophic aortic valves are included, it becomes a relatively common cause of aortic regurgitation. In the authors' experience of 313 patients operated for pure chronic aortic regurgitation, approximately 30% had dystrophic lesions and this was the second most common cause of aortic regurgitation after acute rheumatic fever. The clinical presentation is variable: excluding annulo-aortic ectasia, the other features of dystrophic aortic regurgitation are less well known. Eighty-nine cases without aneurysm of the ascending thoracic aorta were recensed and analysed in a French Cooperative study. They were divided into two groups with respect to the diameter of the ascending aorta measured by echocardiography. The incidence of late postoperative complications of the ascending aorta was higher in patients with a dilated aorta. The diagnosis of dystrophic aortic regurgitation is easy in patients with an aneurysm of the ascending aorta: in other cases, transoesophageal echocardiography is very useful for evaluating the valvular lesions. Surgical treatment of pure dystrophic aortic regurgitation with an aneurysm of the ascending aorta is well established but the best management of aortic regurgitation associated with only mildly dilated aorta is debatable.
虽然营养不良性主动脉瓣关闭不全被认为是一种罕见病症,但如果将通常伴有主动脉根部扩张的囊性中层坏死所致主动脉瓣关闭不全以及营养不良性主动脉瓣所致主动脉瓣关闭不全包括在内,它就成为主动脉瓣关闭不全相对常见的病因。根据作者对313例接受单纯慢性主动脉瓣关闭不全手术患者的经验,约30%患有营养不良性病变,这是继急性风湿热之后主动脉瓣关闭不全的第二大常见病因。临床表现多样:除主动脉根部扩张外,营养不良性主动脉瓣关闭不全的其他特征鲜为人知。在一项法国合作研究中,对89例无升主动脉瘤的病例进行了统计和分析。根据超声心动图测量的升主动脉直径将他们分为两组。升主动脉扩张患者术后晚期并发症的发生率较高。对于有升主动脉瘤的患者,营养不良性主动脉瓣关闭不全的诊断很容易:在其他情况下,经食管超声心动图对评估瓣膜病变非常有用。对于伴有升主动脉瘤的单纯营养不良性主动脉瓣关闭不全,手术治疗已很成熟,但对于仅伴有轻度扩张主动脉的主动脉瓣关闭不全的最佳处理方法仍有争议。