Iserson K V, Reeter A K
Ann Emerg Med. 1984 Feb;13(2):97-100. doi: 10.1016/s0196-0644(84)80569-7.
The ability to replace fluids rapidly is frequently the limiting factor in the survivability of trauma patients. We describe a fluid infusion system that provides approximately a fourfold increase in flow rates over currently available percutaneous systems. It incorporates a 14 French (4.5-mm internal diameter) catheter introduced into a central vein by the Seldinger technique, and a manifold that allows fluid from five separate IV bags to flow into the patient through one line. In vitro tests demonstrated a gravity flow rate of more than 850 mL/min normal saline and a flow rate under pressure of more than 2.0 L/min. Packed red blood cells diluted to 42% hematocrit flowed at 1,725 mL/min under pressure. In vivo testing in dogs demonstrated a maximum gravity flow rate of approximately 650 mL/min, and a pressurized flow rate of more than 1,600 mL/min normal saline. No unusual sequelae of large-bore catheterization were detected.
快速补充液体的能力常常是创伤患者生存能力的限制因素。我们描述了一种输液系统，其流速比目前可用的经皮系统提高了约四倍。它包括一根通过Seldinger技术插入中心静脉的14法式（内径4.5毫米）导管，以及一个歧管，该歧管允许来自五个独立静脉输液袋的液体通过一条管路流入患者体内。体外测试表明，生理盐水的重力流速超过850毫升/分钟，加压流速超过2.0升/分钟。稀释至血细胞比容为42%的浓缩红细胞在压力下的流速为1725毫升/分钟。在犬类动物身上进行的体内测试表明，最大重力流速约为650毫升/分钟，生理盐水的加压流速超过1600毫升/分钟。未检测到与大口径导管插入相关的异常后遗症。
