儿童血浆胆碱酯酶活性与琥珀酰胆碱所致呼吸暂停的持续时间
Plasma cholinesterase activity and the duration of suxamethonium apnoea in children.
作者信息
Mirakhur R K, Elliott P, Lavery T D
出版信息
Ann R Coll Surg Engl. 1984 Jan;66(1):43-5.
Abstract
Plasma cholinesterase activity and the duration of suxamethonium apnoea were studied in 89 children and in 15 adults for comparison. Whereas the level of cholinesterase activity was not different in the two groups, children showed a significantly shorter duration of apnoea. There was poor correlation between the enzyme activity and duration of apnoea. The shorter duration of action of suxamethonium may be due to the larger volume of extracellular fluid in children.
摘要
为作比较，对89名儿童和15名成人的血浆胆碱酯酶活性及琥珀酰胆碱所致呼吸暂停的持续时间进行了研究。虽然两组的胆碱酯酶活性水平无差异，但儿童的呼吸暂停持续时间明显较短。酶活性与呼吸暂停持续时间之间的相关性较差。琥珀酰胆碱作用持续时间较短可能是由于儿童细胞外液量较大。
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