Kneale G W, Mancuso T F, Stewart A M
Br J Ind Med. 1984 Feb;41(1):9-14. doi: 10.1136/oem.41.1.9.
This paper continues the series by Mancuso, Stewart, and Kneale (MSK) on studies of cancer risks for radiation workers at Hanford. It concentrates on the statistical problems posed by the need to estimate and control for job related mortality risks when there are several changes of occupation and no certainty about how different occupations are related to two socioeconomic factors which have strong health associations--namely, education and income. The final conclusion is that for tissues which are sensitive to cancer induced by radiation there is a risk of cancer for Hanford exposures whose dose response is curvilinear with long latency and increasing effect with increasing exposure age.
本文延续了曼库索、斯图尔特和克尼尔（MSK）关于汉福德辐射工作者癌症风险研究的系列文章。它聚焦于在存在多次职业变动且不确定不同职业如何与两个对健康有强烈关联的社会经济因素（即教育和收入）相关的情况下，估计和控制与工作相关的死亡风险时所产生的统计问题。最终结论是，对于对辐射诱发癌症敏感的组织，汉福德暴露存在癌症风险，其剂量反应呈曲线状，潜伏期长，且随着暴露年龄的增加影响增大。
