Britton S, Eklund A E, Bird A G
Gastroenterology. 1978 Aug;75(2):218-20.
The local lymph node in Crohn's disease contains killer (K) cells which are able to lyse antibody-coated heterologous target cells. K cells are not found in mesenteric lymph nodes from control patients not suffering from Crohn's disease, whereas they are regularly found in similar amounts in the peripheral blood of both control and patients with Crohn's disease. Even mesenteric lymph node cells from areas not macroscopically affected by inflammatory disease show increased K cell activity as compared to control lymph node lymphocytes, suggesting a generalized mesenteric lymph node involvement with regard to K activity in Crohn's disease.
克罗恩病患者的局部淋巴结含有杀伤（K）细胞，这些细胞能够裂解抗体包被的异源靶细胞。在未患克罗恩病的对照患者的肠系膜淋巴结中未发现K细胞，而在对照患者和克罗恩病患者的外周血中均能定期发现数量相似的K细胞。与对照淋巴结淋巴细胞相比，即使是未受炎症性疾病宏观影响区域的肠系膜淋巴结细胞也表现出K细胞活性增加，这表明在克罗恩病中，肠系膜淋巴结在K细胞活性方面存在广泛受累情况。
