Brand S, Hutchinson D W, Donaldson D
Clin Chim Acta. 1984 Jan 31;136(2-3):197-202. doi: 10.1016/0009-8981(84)90292-4.
Albumin Redhill, a variant human albumin with the same C-terminal amino acid as albumin A but with arginine at the N-terminus has been isolated by chromatofocusing from the sera of an English family. Albumin Redhill appears to contain two sites of mutation in its protein chain and is probably a proalbumin. The ability of albumin Redhill to bind Ni(II) or Cu(II) ions is considerably less than that of albumin A.
雷丁白蛋白是一种变异的人白蛋白,其C端氨基酸与白蛋白A相同,但N端为精氨酸。通过色谱聚焦法从一个英国家庭的血清中分离出了雷丁白蛋白。雷丁白蛋白在其蛋白质链中似乎含有两个突变位点,可能是一种前白蛋白。雷丁白蛋白结合镍(II)或铜(II)离子的能力明显低于白蛋白A。