Zhurkov V S, Shram R Ia
Genetika. 1978 May;14(5):824-8.
The dependence of induction of dominant lethal mutations in male mice on the duration of exposure (from 1 to 12 weeks) to 0.01% aqueous solution of cyclophosphamide was studied. The maximal frequency of dominant lethal mutations was observed when males treated were crossed during the first week after the end of exposure. The yield of dominant lethal mutations did not depend on the duration of the exposure of cyclophosphamide.
研究了雄性小鼠显性致死突变的诱导对暴露于0.01%环磷酰胺水溶液的持续时间（从1周到12周）的依赖性。当在暴露结束后的第一周对处理过的雄性小鼠进行交配时，观察到显性致死突变的最大频率。显性致死突变的发生率并不取决于环磷酰胺的暴露持续时间。
