环磷酰胺诱发的一名卵巢癌患者间质性肺炎

Cyclophosphamide-induced interstitial pneumonitis in a patient with ovarian carcinoma.

作者信息

Tsukamoto N, Matsukuma K, Matsuyama T, Kashimura M, Kamura T, Uchino H, Imachi M

出版信息

Gynecol Oncol. 1984 Jan;17(1):41-51. doi: 10.1016/0090-8258(84)90058-1.

Abstract

A 40-year-old female with ovarian cancer being treated with daily oral cyclophosphamide developed fatal interstitial pneumonitis. Autopsy did not show any evidence of ovarian cancer. The review of the literature revealed eight reported cases of cyclophosphamide-induced interstitial pneumonitis and fibrosis. The case is reported to alert gynecologists to this rare but lethal complication of cyclophosphamide.

摘要

一名40岁患有卵巢癌的女性正在接受每日口服环磷酰胺治疗，却患上了致命的间质性肺炎。尸检未发现卵巢癌的任何迹象。文献回顾显示有8例环磷酰胺诱发间质性肺炎和纤维化的报告病例。报告此病例是为了提醒妇科医生注意环磷酰胺这种罕见但致命的并发症。