Foresta C, Ruzza G, Mioni R, Guarneri G, Gribaldo R, Meneghello A, Mastrogiacomo I
Horm Res. 1984;19(1):18-22. doi: 10.1159/000179855.
The bone mineral content was evaluated in 30 male subjects aged between 60 and 90 years using the relief of the percent cortical area (PCA) at the level of the second phalanx of the left-hand index finger, by Garn's method. This was to evaluate the rate of bone loss with increasing age. Testosterone, androstenedione, estrone, 17 beta-estradiol plasma levels were determined in all subjects by the RIA method. 60% of our patients showed increased bone resorption (PCA less than 55%); in these subjects testosterone and androstenedione plasma levels were significantly lower than in subjects not affected by osteoporosis. A positive linear correlation is evident between PCA and testosterone, androstenedione and estrone plasma levels. Thus, like in women, decline of gonadic function determines an increased bone resorption in men too.
采用加恩氏方法，通过左手食指第二指骨水平的皮质面积百分比（PCA）的变化，对30名年龄在60至90岁之间的男性受试者的骨矿物质含量进行了评估。目的是评估随着年龄增长的骨质流失率。采用放射免疫分析法（RIA法）测定了所有受试者的睾酮、雄烯二酮、雌酮、17β -雌二醇血浆水平。60%的患者骨吸收增加（PCA小于55%）；在这些受试者中，睾酮和雄烯二酮的血浆水平显著低于未受骨质疏松影响的受试者。PCA与睾酮、雄烯二酮和雌酮的血浆水平之间存在明显的正线性相关性。因此，与女性一样，性腺功能减退也会导致男性骨吸收增加。
