Donegan J O, Wood M D
Laryngoscope. 1984 Feb;94(2 Pt 1):206-9. doi: 10.1288/00005537-198402000-00011.
Granulomatous diseases caused by infectious agents are being seen more frequently than before. Infection with Histoplasma capsulatum is one such granulomatous disease. This condition may have protean manifestations, with involvement of the larynx of particular interest to the Otolaryngologist. Histoplasmosis of the larynx may present difficult diagnostic problems and may closely mimic carcinoma. A case of histoplasmosis of the larynx treated at the University of Cincinnati Medical Center is presented and used to highlight the mode of presentation and the management of this particular disease. The clinical presentation of histoplasmosis is discussed with emphasis on involvement of the upper aerodigestive tract. The diagnostic tests of practical value are outlined. Amphotericin B is the treatment for this disease entity.
由感染因子引起的肉芽肿性疾病比以往更为常见。荚膜组织胞浆菌感染就是这样一种肉芽肿性疾病。这种病症可能有多种表现形式，喉受累尤其引起耳鼻喉科医生的关注。喉组织胞浆菌病可能带来诊断难题，且可能与癌极为相似。本文介绍了一例在辛辛那提大学医学中心接受治疗的喉组织胞浆菌病病例，并以此突出该特定疾病的表现方式及治疗方法。文中讨论了组织胞浆菌病的临床表现，重点是上呼吸道和消化道受累情况。概述了具有实际价值的诊断测试。两性霉素B是治疗该疾病实体的药物。
