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[意向性及动作性肌阵挛揭示职业性汞中毒]

[Intention and action myoclonus disclosing occupational mercury poisoning].

作者信息

Roullet E, Nizou R, Jedynak P, Lhermitte F

出版信息

Rev Neurol (Paris). 1984;140(1):55-8.

PMID:6695124
Abstract

A 58-year-old laboratory-glassware manufacturer was referred to hospital because of coarse "tremor" of the upper extremities of 16-months-duration. Examination showed severe intention and action myoclonus, confirmed by electromyographic recording, slight memory impairment but was otherwise normal. Mercury levels were high in blood and urine (not in CSF) and, as other causes of myoclonus were excluded, inorganic mercury poisoning, was diagnosed. Only slight unilateral intention tremor persisted after dimercaprol treatment. Inhalation of mercury vapor was the mode of contamination. Myoclonus is the hallmark of severe inorganic mercury intoxication, the main clinical and pathological aspects of which are briefly discussed.

摘要

一名58岁的实验室玻璃器皿制造商因上肢出现持续16个月的粗大“震颤”而被转诊至医院。检查发现有严重的意向性和动作性肌阵挛,经肌电图记录证实,有轻微的记忆障碍,但其他方面正常。血液和尿液(脑脊液中未检测到)中的汞含量很高,由于排除了其他导致肌阵挛的原因,诊断为无机汞中毒。二巯丙醇治疗后仅遗留轻微的单侧意向性震颤。汞蒸气吸入是污染途径。肌阵挛是严重无机汞中毒的标志,本文简要讨论了其主要的临床和病理方面。

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