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血清因子与冈比亚锥虫在采采蝇中的感染成熟

Serum factors and the maturation of Trypanosoma congolense infections in Glossina morsitans.

作者信息

Maudlin I, Kabayo J P, Flood M E, Evans D A

出版信息

Z Parasitenkd. 1984;70(1):11-9. doi: 10.1007/BF00929570.

DOI:10.1007/BF00929570
PMID:6695534
Abstract

Removal of certain components from pig or cow blood greatly reduces the maturation rate of Trypanosoma congolense infections in Glossina morsitans fed on such diets. In particular, delipidation of serum has the same effect as complete removal of dietary serum with few midgut infections reaching maturity. The addition of gamma-globulin to red cells partially restores the ability of immature infections to transform suggesting that serum lipids or other serum factors are not acting directly on midgut trypanosome metabolism but indirectly through interactions between dietary constituents and the flies' metabolic processes. As susceptibility to T. congolense infection is known to be maternally inherited in G. morsitans, it is suggested that serum factors act through the flies' symbionts to induce maturation in midgut infections.

摘要

从猪血或牛血中去除某些成分,会大大降低以这种饮食为食的采采蝇感染刚果锥虫的成熟率。特别是,血清去脂的效果与完全去除饮食中的血清相同,很少有中肠感染能发育成熟。向红细胞中添加γ-球蛋白可部分恢复未成熟感染的转化能力,这表明血清脂质或其他血清因子并非直接作用于中肠锥虫的代谢,而是通过饮食成分与苍蝇代谢过程之间的相互作用间接发挥作用。由于已知采采蝇对刚果锥虫感染的易感性是母系遗传的,因此有人提出血清因子通过苍蝇的共生体发挥作用,从而诱导中肠感染发育成熟。

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本文引用的文献

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THE HOSTS OF GLOSSINA AS THE MAIN FACTOR AFFECTING TRYPANOSOME INFECTION RATES OF TSETSE FLIES IN NIGERIA.作为影响尼日利亚采采蝇锥虫感染率的主要因素的舌蝇宿主
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