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冈比亚舌蝇对刚果锥虫感染的易感和抗性品系的选择及其对不同致病性锥虫种类的易感性

Selection of susceptible and refractory lines of Glossina morsitans centralis for Trypanosoma congolense infection and their susceptibility to different pathogenic Trypanosoma species.

作者信息

Moloo S K, Kabata J M, Waweru F, Gooding R H

机构信息

International Livestock Research Institute (ILRI), Nairobi, Kenya.

出版信息

Med Vet Entomol. 1998 Oct;12(4):391-8. doi: 10.1046/j.1365-2915.1998.00128.x.

DOI:10.1046/j.1365-2915.1998.00128.x
PMID:9824823
Abstract

In a single generation of selection, two lines of Glossina morsitans centralis were established that differed significantly in susceptibility to Trypanosoma congolense clone IL 1180. Reciprocal crosses demonstrated that susceptibility was a maternally inherited trait. Differences between the lines, to all phases of the trypanosome infection, were maintained for eight generations, whereas differences in susceptibility to midgut infections were maintained for twenty-eight generations. Thereafter, the lines did not differ in susceptibility to Trypanosoma congolense IL 1180. Susceptibility to infections with Trypanosoma congolense IL 1180 was only a weak predictor of susceptibility to T. congolense clones IL 13-E3 and K60/1, as well as clone T. brucei brucei STIB 247-L. However, the susceptible and refractory lines displayed these phenotypes when tested with Trypanosoma vivax, indicating that the factors that affect susceptibility to trypanosomes are expressed both within and outside the midgut.

摘要

在一代选择中,建立了两系冈比亚采采蝇,它们对刚果锥虫克隆IL 1180的易感性存在显著差异。正反交实验表明,易感性是一种母系遗传性状。这两个品系在锥虫感染各阶段的差异持续了八代,而对中肠感染易感性的差异则持续了二十八代。此后,这两个品系对刚果锥虫IL 1180的易感性不再有差异。对刚果锥虫IL 1180感染的易感性只是对刚果锥虫克隆IL 13 - E3和K60/1以及布氏锥虫克隆STIB 247 - L易感性的一个弱预测指标。然而,在用间日锥虫进行测试时,易感品系和抗性品系都表现出了这些表型,这表明影响对锥虫易感性的因素在中肠内外均有表达。

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