Lipson L G
Am J Cardiol. 1984 Jan 27;53(3):46A-50A. doi: 10.1016/0002-9149(84)90836-1.
Hypertension occurs 2 to 3 times more frequently in diabetic persons than in nondiabetic persons. Care must be taken in treating hypertension in diabetic patients because the choice of antihypertensive agent may worsen the diabetic state or its complications or cause additional health problems for the patient. Sexual dysfunction is a common problem in diabetic patients; however, diabetes need not be the cause. Diabetic men with hypertension have an increased sensitivity to the side effect of sexual dysfunction, which occurs from the use of centrally acting antihypertensive agents. By using prazosin, an alpha 1-adrenergic blocking agent, this cause of sexual dysfunction was eliminated. The reasons for the increased prevalence of hypertension in diabetic patients are discussed and a rational approach is given for the treatment of elevated blood pressure in these individuals.
糖尿病患者患高血压的频率比非糖尿病患者高2至3倍。治疗糖尿病患者的高血压时必须谨慎，因为抗高血压药物的选择可能会使糖尿病病情或其并发症恶化，或给患者带来其他健康问题。性功能障碍是糖尿病患者的常见问题；然而，糖尿病不一定是其病因。患有高血压的糖尿病男性对性功能障碍副作用的敏感性增加，这种副作用是由使用中枢性抗高血压药物引起的。通过使用α1肾上腺素能阻断剂哌唑嗪，消除了性功能障碍的这一病因。文中讨论了糖尿病患者高血压患病率增加的原因，并给出了治疗这些个体血压升高的合理方法。
