Vertes D, Axelsson A, Hornstrand C, Nilsson P
Arch Otolaryngol. 1984 Feb;110(2):111-5. doi: 10.1001/archotol.1984.00800280045014.
Short- and long-term changes in the cochlear vasculature and long-term changes in the sensorineuroepithelium were studied in guinea pigs after they were exposed to impulse noise. Vessel histology and cochlear hair cell loss were assessed, using a surface-preparation technique, and the results showed considerable variability. Hair cell loss and radial tears in the organ of Corti were a common finding in the animals killed four weeks after impulse-noise exposure. Impulse-noise exposure resulted in few cochlear vascular changes in the acutely and chronically affected groups. Compared with the results of our previous studies using continuous-noise exposure of different characteristics and in different mammals, this impulse-noise experiment resulted in a nonsignificant damaging effect on the cochlear vasculature.
在豚鼠暴露于脉冲噪声后，研究了其耳蜗血管的短期和长期变化以及感觉神经上皮的长期变化。使用表面制备技术评估血管组织学和耳蜗毛细胞损失，结果显示出相当大的变异性。在脉冲噪声暴露四周后处死的动物中，耳蜗毛细胞损失和柯蒂氏器中的放射状撕裂是常见现象。在急性和慢性受影响组中，脉冲噪声暴露导致耳蜗血管变化较少。与我们之前使用不同特性的连续噪声暴露以及在不同哺乳动物中进行的研究结果相比，该脉冲噪声实验对耳蜗血管造成的损伤作用不显著。
