核仁组织区容易易位到缺失的染色体上吗？
Are NORs easily translocated to deleted chromosomes?
作者信息
Zankl H, Huwer H
出版信息
Hum Genet. 1978 Jun 9;42(2):137-42. doi: 10.1007/BF00283633.
The karyotype of two human meningiomas are reported in which, besides other aberrations, a deleted chromosome 1 and 6 could be observed. In these chromosomes most of the short arm is missing. After silver staining for the detection of NORs, not only the satellite regions of most of the acrocentric chromosomes were stained but also the deleted ends of chromosomes 1 and 6. Besides other explanations for this unusual NOR-staining, the possibility is discussed that NORs of acrocentric chromosomes are easily translocated to deleted chromosomes.
本文报告了两例人类脑膜瘤的核型，除其他畸变外，还观察到1号和6号染色体缺失。在这些染色体中，大部分短臂缺失。经过银染以检测核仁组织区（NORs）后，不仅大多数近端着丝粒染色体的随体区域被染色，1号和6号染色体的缺失末端也被染色。除了对这种异常NOR染色的其他解释外，还讨论了近端着丝粒染色体的NORs易转移到缺失染色体上的可能性。
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