Rubio C A
Dis Colon Rectum. 1984 Mar;27(3):182-6. doi: 10.1007/BF02555670.
Colectomy specimens from 62 patients (22 with ulcerative colitis, 20 with Crohn's disease of the colon, and 20 with invasive adenocarcinoma [without inflammatory bowel disease]) were reviewed for the presence of ectopic colonic mucosa. One or more foci of ectopic colonic mucosa were found in 16 of the 22 specimens (72 per cent) with ulcerative colitis and in 11 of the 20 specimens (55 per cent) with Crohn's disease of the colon. None of the 20 specimens having adenocarcinoma (without chronic inflammatory bowel disease) had ectopic colonic epithelium. The presence of ectopic colonic mucosa was found to be dependent on the age of the patients (more frequent among younger patients) and on the number of sections per specimen. One adenocarcinoma in a case of long-standing ulcerative colitis had apparently originated in ectopic colonic mucosa.
对62例患者的结肠切除术标本进行了检查，以确定是否存在异位结肠黏膜，其中22例为溃疡性结肠炎患者，20例为结肠克罗恩病患者，20例为浸润性腺癌患者（无炎症性肠病）。在22例溃疡性结肠炎标本中有16例（72%）发现一个或多个异位结肠黏膜病灶，在20例结肠克罗恩病标本中有11例（55%）发现异位结肠黏膜病灶。20例腺癌标本（无慢性炎症性肠病）均未发现异位结肠上皮。发现异位结肠黏膜的存在取决于患者的年龄（在年轻患者中更常见）和每个标本的切片数量。1例长期溃疡性结肠炎患者的腺癌显然起源于异位结肠黏膜。
