Ferulano G P, Danzi M, Abate S, Fresini A, Vanni L, Califano G
Eur Surg Res. 1984;16(2):127-30. doi: 10.1159/000128398.
Anastomotic leakage after colonic resection still remains a troublesome complication of major clinical significance. Systemic (nutritional status, blood viscosity) or local factors (contamination by local germs, suture technique) seems to be implicated in the healing process of the suture line. The CO2 laser as a cutting procedure in colonic resection should provide a useful tool for its accuracy and the bactericidal properties. We have tested the strength of an end-to-end anastomosis of rat colon resected by CO2 laser, scalpel and diathermy, respectively, by measuring the bursting pressures at different postoperative days. The present study shows that the use of CO2 laser resulted in a significant increase of colonic bursting pressure at the anastomotic site.
结肠切除术后的吻合口漏仍是具有重大临床意义的棘手并发症。全身因素（营养状况、血液黏稠度）或局部因素（局部细菌污染、缝合技术）似乎与吻合口的愈合过程有关。二氧化碳激光作为结肠切除术中的一种切割方法，因其精确性和杀菌特性应能提供一种有用的工具。我们分别通过测量不同术后天数的破裂压力，测试了用二氧化碳激光、手术刀和透热法切除的大鼠结肠端端吻合口的强度。本研究表明，使用二氧化碳激光可使吻合部位的结肠破裂压力显著增加。
