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恶性黑色素瘤多发颅内转移伴长期生存。病例报告。

Multiple intracranial metastases of malignant melanoma with long-term survival. Case report.

作者信息

Fernandez E, Maira G, Puca A, Vignati A

出版信息

J Neurosurg. 1984 Mar;60(3):621-4. doi: 10.3171/jns.1984.60.3.0621.

DOI:10.3171/jns.1984.60.3.0621
PMID:6699709
Abstract

The authors present a case of multiple brain metastases and an extracranial secondary localization from malignant melanoma. The patient was operated on three times for the intracranial masses and had a 49-month survival with a good quality of life after the first of the three operations. She lived a total of 80 months from the time of diffusion of the primary tumor. The course of malignant melanoma is unpredictable, and long-term survival can be achieved in some cases, even in the presence of multiple brain metastases.

摘要

作者报告了一例恶性黑色素瘤发生多处脑转移及颅外继发转移的病例。该患者因颅内肿块接受了三次手术,在第一次手术后存活了49个月,生活质量良好。从原发肿瘤扩散时起,她总共存活了80个月。恶性黑色素瘤的病程不可预测,即使存在多处脑转移,在某些情况下仍可实现长期生存。

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引用本文的文献

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Prolonged survival after surgical resection of cerebral metastasis from melanoma with multisystemic metastasis already present: a case report and literature review.黑色素瘤脑转移已出现多系统转移情况下手术切除后的长期生存:一例报告及文献综述
Sao Paulo Med J. 2018 Jul-Aug;136(4):372-375. doi: 10.1590/1516-3180.2017.0003090317. Epub 2017 Aug 21.
2
Somatic and germline analyses of a long term melanoma survivor with a recurrent brain metastasis.一名患有复发性脑转移的长期黑色素瘤幸存者的体细胞和生殖系分析。
BMC Cancer. 2015 Nov 23;15:926. doi: 10.1186/s12885-015-1927-0.
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Simultaneous surgical resections of two distant metastatic malignant melanoma lesions--case report.
同时手术切除两个远处转移性恶性黑色素瘤病灶——病例报告
Nagoya J Med Sci. 2012 Feb;74(1-2):173-9.
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Multiple intracranial melanoma metastases: case report and review of the literature.多发性颅内黑色素瘤转移:病例报告及文献综述
J Neurooncol. 2009 Jul;93(3):413-20. doi: 10.1007/s11060-008-9785-0. Epub 2009 Feb 1.
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Cerebral metastases of cutaneous melanoma.皮肤黑色素瘤的脑转移
Br J Cancer. 1997;76(2):256-9. doi: 10.1038/bjc.1997.371.