对90例膀胱癌膀胱切除标本的连续切片进行分析。

Analysis of 90 step-sectioned cystectomized specimens of bladder cancer.

作者信息

Kakizoe T, Matsumoto K, Nishio Y, Kishi K

出版信息

J Urol. 1984 Mar;131(3):467-72. doi: 10.1016/s0022-5347(17)50454-1.

Abstract

For systematic understanding of papillary superficial carcinoma and nonpapillary invasive carcinoma of the bladder 90 cystectomized specimens of transitional cell carcinoma of the bladder were analyzed by step-section. From gross and microscopic observations bladder cancer was classified into 3 types: type 1--multiple papillary superficial carcinomas with or without small areas of dysplasia or carcinoma in situ, type 2--multiple coexistent papillary and nonpapillary carcinomas with widespread dysplasia and carcinoma in situ, and type 3--solitary nonpapillary invasive carcinoma without dysplasia and carcinoma in situ. Actuarial 5-year survival rates for types 1 to 3 were 97, 50 and 17 per cent, respectively. Although this classification is somewhat overlapping and there is a bias that basic data are obtained from the cystectomized specimens, we believe that such an analysis is necessary for considering the histogenesis and progression of human bladder cancer.

摘要

为系统了解膀胱乳头状浅表癌和非乳头状浸润癌，对90例膀胱移行细胞癌膀胱切除标本进行了连续切片分析。通过大体和显微镜观察，膀胱癌分为3型：1型——多个乳头状浅表癌，伴有或不伴有小面积发育异常或原位癌；2型——多个乳头状癌和非乳头状癌并存，伴有广泛发育异常和原位癌；3型——孤立性非乳头状浸润癌，无发育异常和原位癌。1至3型的实际5年生存率分别为97%、50%和17%。尽管这种分类存在一定重叠，且存在从膀胱切除标本获取基础数据的偏差，但我们认为这种分析对于考虑人类膀胱癌的组织发生和进展是必要的。