Allsop J R, Wolfe R R, Burke J F
J Appl Physiol Respir Environ Exerc Physiol. 1978 Jul;45(1):137-9. doi: 10.1152/jappl.1978.45.1.137.
We have described a technique whereby the time necessary to reach an equilibrium enrichment of expired CO2 during a primed-constant infusion of [U-13C]glucose was shortened from 7 to 8 h to 1 hour or less. We applied the theory of the primed-constant infusion technique to the bicarbonate pool, with the "constant infusion" of labeled carbon dioxide originating from oxidation of the infused [13C]glucose rather than from a labeled infusion of bicarbonate.
我们已经描述了一种技术，通过该技术，在给予负荷量并持续输注[U-13C]葡萄糖期间，呼出二氧化碳达到平衡富集所需的时间从7至8小时缩短至1小时或更短。我们将负荷量并持续输注技术的理论应用于碳酸氢盐池，其中标记二氧化碳的“持续输注”源自输注的[13C]葡萄糖的氧化，而非源自标记的碳酸氢盐输注。
