Jaraquemada D, Alonso A, Awad J, D'Amaro J, Ollier W, Doyle P, Okoye R C, Williams E, Festenstein H, Lian F
Tissue Antigens. 1984 Jan;23(1):23-32. doi: 10.1111/j.1399-0039.1984.tb00004.x.
The frequencies of the HLA-A, B, C, D, DR and MB antigens have been determined in a homogeneous Shanghai Chinese population. Comparisons with the HLA-A and -B frequencies in other subsets of the Chinese population revealed some marked differences. No comparisons were possible for the D, DR and MB antigens since there were no previous studies of the antigens in those loci. We suggest that studies of the Chinese population should be confined to clearly defined homogeneous subsets. In this manner, the confounding effect of population heterogeneity may be avoided, and it is this heterogeneity which calls for extensive surveys of the huge Chinese population.
已在上海一个同质化的中国人群中测定了HLA - A、B、C、D、DR和MB抗原的频率。与中国人群其他亚组中的HLA - A和 - B频率比较显示出一些显著差异。由于之前没有关于那些位点抗原的研究，所以无法对D、DR和MB抗原进行比较。我们建议对中国人群的研究应局限于明确界定的同质化亚组。通过这种方式，可以避免人群异质性的混杂效应，而正是这种异质性使得有必要对庞大的中国人群进行广泛调查。
