Borodina N P, Klenova A V, Voskoboĭnik A D, Shevliagin V Ia
Vopr Onkol. 1984;30(2):80-4.
Human papovavirus isolated from human malignant paraganglioma was found to have pathologic relevance to golden hamsters of varying age inducing sarcomas in adults, when given intracerebrally, and lesions of central nervous system in newborns inoculated subcutaneously. T-antigen, immunologically related to that of SV40 was detected in tumor cells. Infectious papovavirus, identical to human one, was isolated from brain tissues of sick hamsters.
从人类恶性副神经节瘤中分离出的人乳头多瘤空泡病毒,被发现与不同年龄的金黄地鼠具有病理相关性:对成年地鼠脑内接种时可诱发肉瘤,对新生地鼠皮下接种时可诱发中枢神经系统病变。在肿瘤细胞中检测到与SV40的T抗原具有免疫相关性的T抗原。从患病地鼠的脑组织中分离出了与人乳头多瘤空泡病毒相同的传染性乳头多瘤空泡病毒。