Garland T A, Innes D J, Fechner R E
Am J Clin Pathol. 1984 Apr;81(4):436-41. doi: 10.1093/ajcp/81.4.436.
Salivary duct carcinoma (SDC) is a histologically distinctive neoplasm of the parotid gland. The criteria for the diagnosis of SDC are circumscribed epithelial nests having a papillary, cribriform, and/or solid architecture coupled with central necrosis. The infiltrating cancer can be papillary, resembling the intraductal component or have a nonspecific, undifferentiated pattern. The authors are presenting four cases and compare them with 11 other acceptable cases from the literature. The neoplasm occurs beyond the age of 50 (median 63 years) and has a dismal prognosis with nearly two-thirds of the patients developing distant metastases. All surviving patients have been treated with combined parotidectomy and radiotherapy.
涎腺导管癌(SDC)是腮腺一种具有独特组织学特征的肿瘤。SDC的诊断标准为具有乳头、筛状和/或实性结构并伴有中央坏死的局限性上皮巢。浸润性癌可为乳头状,类似于导管内成分,或具有非特异性、未分化模式。作者报告了4例病例,并将其与文献中另外11例可接受的病例进行比较。该肿瘤发生于50岁以上(中位年龄63岁),预后较差,近三分之二的患者会发生远处转移。所有存活患者均接受了腮腺切除术和放疗联合治疗。