A family history study of schizophrenia-related personality disorders.

This study examined whether the family history method can be used to detect cases of schizophrenia-related personality disorder in the families of schizophrenic patients. After proposing specific family history criteria for this diagnosis, the authors applied these criteria in a blind family history study and found that schizophrenia-related personality disorders were significantly more common in the first-degree relatives of schizophrenic patients than in the relatives of medically ill controls.