Oláh I, Glick B
Anat Rec. 1984 Feb;208(2):243-52. doi: 10.1002/ar.1092080211.
We have described an extramedullary myelopoietic tissue located in the wall of the yolk sac. This myelopoietic site is absent at hatch and it produces only granulocytic and monocytic cells during the regression of the yolk sac from 2 to 7 weeks of age. The granulocytic and monocytic cells are located in two distinct zones. The monocytic cells migrate close to the lumen of the yolk sac where they may fuse and form giant cells. There are no mature granulocytes present. Cell migration has not been observed. Therefore, the fate and function of the young granulocytic cells are unknown. In this extramedullary myelopoietic tissue, the absence of erythrocyte and thrombocyte formation may indirectly suggest that these cells develop together in sinuses that are lacking in the wall of the yolk sac.
我们描述了一种位于卵黄囊壁的髓外造血组织。这种造血部位在孵化时不存在，在2至7周龄卵黄囊退化期间仅产生粒细胞和单核细胞。粒细胞和单核细胞位于两个不同的区域。单核细胞迁移至靠近卵黄囊腔的位置，在那里它们可能融合并形成巨细胞。不存在成熟的粒细胞。未观察到细胞迁移。因此，年轻粒细胞的命运和功能尚不清楚。在这种髓外造血组织中，缺乏红细胞和血小板生成可能间接表明这些细胞在卵黄囊壁缺乏的血窦中共同发育。
