McCabe R E, Baldwin J C, McGregor C A, Miller D C, Vosti K L
Ann Intern Med. 1984 Apr;100(4):525-7. doi: 10.7326/0003-4819-100-4-525.
Prosthetic valve endocarditis due to Legionella pneumophila occurred in a woman who had aortic and mitral valve replacements with porcine xenografts. During surgery for persistent fever and aortic regurgitation due to presumed endocarditis, she had vegetations involving both the aortic and mitral valve prostheses with a circumferential abscess of the aortic annulus. Cultures, Dieterle stain, and direct fluorescent antibody stain of valve tissue, and subsequent measurements of serum antibody levels confirmed L. pneumophila as the infecting organism. This infection occurred in the absence of pneumonia. Legionella pneumophila must be considered a potential cause of culture-negative prosthetic valve endocarditis and should be sought in appropriate clinical circumstances.
一名接受猪异种移植物主动脉和二尖瓣置换术的女性发生了由嗜肺军团菌引起的人工瓣膜心内膜炎。在因疑似心内膜炎导致持续发热和主动脉瓣关闭不全而进行的手术中，她的主动脉和二尖瓣人工瓣膜均有赘生物，且主动脉瓣环有环形脓肿。瓣膜组织的培养、Dietertle染色和直接荧光抗体染色，以及随后血清抗体水平的检测证实嗜肺军团菌为感染病原体。此次感染发生时并无肺炎。嗜肺军团菌必须被视为培养阴性人工瓣膜心内膜炎的潜在病因，在适当的临床情况下应进行排查。
