Grizzard W S, Torczynski E, Char D H
Arch Ophthalmol. 1984 Apr;102(4):576-8. doi: 10.1001/archopht.1984.01040030454025.
A 47-year-old man with a large (20 X 20 X 12-mm) choroidal melanoma in his only eye was treated with helium ion radiation. The patient retained 6/7.5 visual acuity for 2 1/2 years before he was killed in an automobile accident. The eye was ruptured at the time of death; however, histopathologic examination of the eye revealed no residual tumor. The residual ocular mass was composed of eosinophilic amorphous material and macrophages. Necropsy failed to reveal any evidence of metastasis at the time of death. Helium ion charged-particle irradiation in this case was able to completely eradicate the tumor while preserving useful vision.
一名47岁男性，单眼患有巨大（20×20×12毫米）脉络膜黑色素瘤，接受了氦离子放射治疗。该患者在因车祸丧生之前的2年半时间里，视力一直保持在6/7.5。死亡时眼睛已破裂；然而，对该眼睛的组织病理学检查未发现残留肿瘤。残留的眼部肿块由嗜酸性无定形物质和巨噬细胞组成。尸检未发现死亡时存在转移的任何证据。在该病例中，氦离子带电粒子照射能够在保留有用视力的同时完全根除肿瘤。
