Char D H, Castro J R, Quivey J M, Chen G T, Lyman J T, Stone R D, Irvine A R, Barricks M, Crawford J B, Hilton G F, Lonn L I, Schwartz A
Ophthalmology. 1980 Jun;87(6):565-70. doi: 10.1016/s0161-6420(80)35195-6.
Nine patients with choroidal melanomas were treated with helium ion charged particle irradiation. No patient demonstrated tumor enlargement, and most lesions followed for more than five months have demonstrated tumor shrinkage. The most effective method of choroidal melanoma management is unclear. Heavy charged particle irradiation may be more applicable and have less ocular morbidity associated with it in either radioactive plaques or photocoagulation.
9例脉络膜黑色素瘤患者接受了氦离子带电粒子照射治疗。没有患者出现肿瘤增大,并且大多数随访超过5个月的病变都显示出肿瘤缩小。脉络膜黑色素瘤最有效的治疗方法尚不清楚。在放射性敷贴或光凝治疗中,重带电粒子照射可能更适用且与之相关的眼部发病率更低。