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梨状窦癌的高剂量放射治疗

High-dose radiation therapy in carcinoma of the pyriform sinus.

作者信息

Ahmad K, Fayos J V

出版信息

Cancer. 1984 May 15;53(10):2091-4. doi: 10.1002/1097-0142(19840515)53:10<2091::aid-cncr2820531016>3.0.co;2-r.

DOI:10.1002/1097-0142(19840515)53:10<2091::aid-cncr2820531016>3.0.co;2-r
PMID:6704897
Abstract

In a retrospective analysis of 61 patients with carcinoma of the pyriform sinus, treated primarily with high doses of radiation therapy with surgery reserved for persistent or recurrent tumor, survival rates of 56.5% and 12.4% were found in Stages III and IV, respectively. The two patients with Stage II disease were cured. There were no Stage I patients. The local control of T4 lesions and N2-3 lesions, as well as the survival of patients with Stage IV disease, is poor with radiation alone. This points out the necessity of combining irradiation with surgery and/or chemotherapy for Stage IV disease. The results in early stages with radiation alone are acceptable.

摘要

在一项对61例梨状窝癌患者的回顾性分析中,主要采用高剂量放射治疗,手术仅用于持续性或复发性肿瘤,Ⅲ期和Ⅳ期患者的生存率分别为56.5%和12.4%。2例Ⅱ期疾病患者治愈。无Ⅰ期患者。单纯放疗对T4病变和N2-3病变的局部控制以及Ⅳ期疾病患者的生存率较差。这表明Ⅳ期疾病有必要将放疗与手术和/或化疗相结合。早期单纯放疗的结果是可以接受的。

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