Tobach E, DeSantis J L, Zucker M B
J Hered. 1984 Jan-Feb;75(1):15-8. doi: 10.1093/oxfordjournals.jhered.a109855.
Fawn-hooded rats have a hemorrhagic disorder known as platelet storage pool deficiency. Parent stocks of Fawn-hooded, Long-Evans, and Wistar (DAB) rats and the progeny of their reciprocal crosses were studied for coat color and percentage 14C-serotonin uptake and secretion by blood platelets. Progeny of Fawn-hooded and Wistar reciprocal crosses were dark- or light-hooded, whereas all reciprocal crosses with the Long-Evans stock were dark-hooded. The light or fawn hood was significantly associated with the reduced serotonin uptake and secretion characteristic of storage pool efficiency.
鹿毛色大鼠有一种出血性疾病,称为血小板储存池缺陷。对鹿毛色、长 Evans 和 Wistar(DAB)大鼠的亲本品系及其正反交后代进行了毛色以及血小板对 14C - 5 - 羟色胺摄取和分泌百分比的研究。鹿毛色大鼠与 Wistar 大鼠正反交的后代为深色或浅色毛,而与长 Evans 品系的所有正反交后代均为深色毛。浅色或鹿毛色与储存池效率降低所特有的 5 - 羟色胺摄取和分泌减少显著相关。