Klein R, Klein B E, Moss S E
Ophthalmology. 1984 Jan;91(1):1-9.
Visual acuity was measured in a population-based study of diabetic retinopathy in southern Wisconsin. Persons diagnosed prior to 30 years of age and taking insulin (younger onset, n = 996) and those diagnosed at 30 years of age or older (older onset, n = 1370) were examined. Best corrected visual acuity was determined using the Early Treatment of Diabetic Retinopathy Study protocol. In the younger onset group, 1.4% had moderate visual impairment (best corrected visual acuity in the better eye of 20/80 to 20/160) and 3.6% were legally blind (visual acuity in the better eye of 20/200 or worse). Visual impairment in this group was associated with older age at examination, longer duration of diabetes, presence of proliferative retinopathy, and presence of senile cataracts. In the older onset group, 3.0% had moderate visual impairment and 1.6% were legally blind. Visual impairment in this group was associated with older age at examination, longer duration of diabetes, presence of senile cataract, presence of macular edema, and proliferative diabetic retinopathy. When assigning causes of impaired vision, diabetic retinopathy was responsible in part for 86% of eyes with visual acuity of 20/200 or worse in younger onset persons and for 33% in older onset persons.
在威斯康星州南部进行的一项基于人群的糖尿病视网膜病变研究中测量了视力。对30岁之前被诊断出糖尿病且正在接受胰岛素治疗的人群(发病较早组,n = 996)以及30岁及以上被诊断出糖尿病的人群(发病较晚组,n = 1370)进行了检查。使用糖尿病视网膜病变早期治疗研究方案确定最佳矫正视力。在发病较早组中,1.4%的人有中度视力损害(较好眼的最佳矫正视力为20/80至20/160),3.6%的人存在法定失明(较好眼的视力为20/200或更差)。该组的视力损害与检查时年龄较大、糖尿病病程较长、增殖性视网膜病变的存在以及老年性白内障的存在有关。在发病较晚组中,3.0%的人有中度视力损害,1.6%的人存在法定失明。该组的视力损害与检查时年龄较大、糖尿病病程较长、老年性白内障的存在、黄斑水肿的存在以及增殖性糖尿病视网膜病变有关。在确定视力受损原因时,糖尿病视网膜病变在发病较早人群中导致86%视力为20/200或更差的眼睛出现视力受损,在发病较晚人群中这一比例为33%。