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印度老年糖尿病患者白内障和青光眼的风险:基于 LASI,第 1 波的横断面研究。

Risk of cataract and glaucoma among older persons with diabetes in India: a cross-sectional study based on LASI, Wave-1.

机构信息

Department of Population and Development, International Institute for Population Sciences, Mumbai, India.

出版信息

Sci Rep. 2023 Jul 24;13(1):11973. doi: 10.1038/s41598-023-38229-z.

Abstract

According to the International Diabetes Federation-2019 estimates, India is home to 77 million diabetic individuals which is projected to grow up to 147.2 million by 2045. Diabetes being a progressive health disorder leads to multiple morbidities and complications including eye diseases and visual impairments. As the burden of diabetes mellitus is increasing, eye problems like cataracts and glaucoma are commonly cited problems among the older adults. In this context, this study aims to provide the public health evidences on diabetes associated burden and risk of developing cataracts and glaucoma among older adults aged 60 and above in India. The analytical sample of this cross-sectional study comprised of 31,464 individuals aged 60 and above. Bivariate cross-tabulation and chi-square test were performed to understand the differential in the prevalence of cataracts and glaucoma by diabetes mellitus including the socio-economic and demographic characteristics of the individuals. Binary logistic regression estimation was executed to estimate the adjusted odds ratio for each of the outcome variables within a multivariate framework. The cataract problem affects more than one-fifth of the older people, while glaucoma affects 2% of them. The prevalence of cataract and glaucoma is 29% among diabetic older adults compared to 22% among non-diabetic persons. In terms of gender, the cataract prevalence is comparatively higher among females (25%) than males (21%). It is important to note that while adjusting for socio-economic and demographic characteristics, the likelihood of cataract (AOR 1.495; p-value < 0.01) and glaucoma (AOR 1.554; p-value < 0.01) is significantly higher among older adults with diabetes than among their counterparts. Medical practitioners should conduct prognosis for diabetic eye problems among patients and raise awareness about the potential risks of developing vision loss, such as cataracts and glaucoma, which are more prevalent among individuals with diabetes.

摘要

根据国际糖尿病联合会 2019 年的估计,印度有 7700 万糖尿病患者,预计到 2045 年将增至 1.472 亿。糖尿病是一种进行性的健康疾病,会导致多种疾病和并发症,包括眼病和视力障碍。随着糖尿病负担的增加,白内障和青光眼等眼部问题在老年人中较为常见。在这种情况下,本研究旨在为公众提供有关印度 60 岁及以上老年人中与糖尿病相关的负担以及白内障和青光眼发病风险的健康证据。本横断面研究的分析样本包括 31464 名 60 岁及以上的人。采用双变量交叉表和卡方检验来了解糖尿病患者白内障和青光眼的患病率差异,包括个体的社会经济和人口统计学特征。在多变量框架内,执行二元逻辑回归估计,以估算每个结果变量的调整后比值比。五分之一以上的老年人有白内障问题,而 2%的老年人有青光眼问题。与非糖尿病患者相比,糖尿病老年患者白内障和青光眼的患病率分别为 29%和 22%。就性别而言,女性(25%)白内障的患病率高于男性(21%)。值得注意的是,在调整社会经济和人口统计学特征后,与非糖尿病患者相比,糖尿病老年患者白内障(优势比 1.495;p 值<0.01)和青光眼(优势比 1.554;p 值<0.01)的发病几率显著更高。医疗保健从业者应在患者中对糖尿病眼病进行预后,并提高对潜在视力丧失风险(如白内障和青光眼)的认识,这些疾病在糖尿病患者中更为普遍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f46/10366202/48fc4347793b/41598_2023_38229_Fig1_HTML.jpg

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