McCarthy J G, Epstein F, Sadove M, Grayson B, Zide B
Plast Reconstr Surg. 1984 Apr;73(4):521-33. doi: 10.1097/00006534-198404000-00001.
A prospective review is presented of 50 patients with one of the craniofacial synostosis syndromes who underwent early interventive craniofacial surgical correction (average age 7.6 months at time of surgery). The study has demonstrated the efficacy and safety of the techniques when employed in the infant. Satisfactory cranio-orbital form was achieved in the majority of the patients, although 10 patients required secondary surgery because of sutural refusion or the development of turricephaly or calvarial contour irregularities. Despite earlier hopes, this surgery did not result in the development of satisfactory occlusal relationships and midfacial form in the craniofacial dysostosis group (Crouzon's, Apert's, etc.). Based on this clinical experience, a surgical treatment plan is presented for the newborn with craniofacial synostosis.
本文对50例患有颅面骨缝早闭综合征之一并接受早期干预性颅面外科矫正手术的患者进行了前瞻性回顾（手术时平均年龄为7.6个月）。该研究证明了这些技术应用于婴儿时的有效性和安全性。大多数患者获得了满意的颅眶形态，尽管有10例患者因骨缝再融合、尖头畸形或颅骨轮廓不规则而需要二次手术。尽管早期抱有希望，但在颅面骨发育不全组（如克鲁宗综合征、阿佩尔综合征等）中，该手术并未产生令人满意的咬合关系和中面部形态。基于这一临床经验，本文提出了针对新生儿颅面骨缝早闭的手术治疗方案。
