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假性脑瘤治疗中的长期颅内压记录

Long-term intracranial pressure recording in the management of pseudotumor cerebri.

作者信息

Gücer G, Viernstein L

出版信息

J Neurosurg. 1978 Aug;49(2):256-63. doi: 10.3171/jns.1978.49.2.0256.

DOI:10.3171/jns.1978.49.2.0256
PMID:671078
Abstract

Long-term monitoring of intracranial pressure (ICP) was used as an aid for the management of four patients with pseudotumor cerebri. After the implantation of a small experimental pressure sensor in the skull, most of the subsequent (ICP measurements were made noninvasively by an external interrogator. During the initial study of the patient, baseline ICP recordings were made in the hospital before treatment. Pressure recordings on a 24-hour basis were continued during treatment, which, depending on the case, was with Diamox (acetazolamide), steroids, or the coperitoneal shunting. After discharge these patients returned weekly over 10 to 22 months for ICP measurement and for ophthalmological examination. Intracranial pressure before treatment showed irregular variations ranging from 100 to 500 mm H2O over a 24-hour period. The efficacy of treatments could be assessed in a few hours by the degree of ICP stabilization. Shunt malfunction was detected by a slow but continuous rise in pressure before full clinical signs were evident.

摘要

对4例假性脑瘤患者进行了长期颅内压(ICP)监测,以辅助治疗。在颅骨内植入一个小型实验性压力传感器后,随后的大多数ICP测量由外部询问器进行无创测量。在对患者进行初步研究期间,在治疗前于医院进行了基线ICP记录。治疗期间持续进行24小时压力记录,根据具体情况,治疗采用醋氮酰胺(乙酰唑胺)、类固醇或脑室腹腔分流术。出院后,这些患者在10至22个月内每周返回进行ICP测量和眼科检查。治疗前颅内压在24小时内显示出不规则变化,范围为100至500 mm H2O。治疗效果可在数小时内通过ICP稳定程度进行评估。在出现明显的完整临床体征之前,通过压力缓慢但持续升高检测到分流故障。

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