Taylor M C, Bradley W E, Bhatia N, Glick M, Haldeman S
Acta Neurol Scand. 1984 Feb;69(2):80-9. doi: 10.1111/j.1600-0404.1984.tb07783.x.
Bowel, bladder and sexual dysfunction are common in multiple sclerosis and are generally attributed to the widespread nature of the involvement of the neuroaxis by the demyelinating plaques. Recently we encountered a specific subset of patients within this group who had characteristic clinical complaints of hesitancy, straining and incomplete voiding, perineal hypesthesia on examination, areflexia by cystometry and colonometry and electrophysiological parameters suggesting involvement of the conus medullaris. This heretofore postulated but undocumented mechanism of neurovisceral dysfunction in multiple sclerosis is detailed and discussed in 2 patients in this report.
肠道、膀胱和性功能障碍在多发性硬化症中很常见，通常归因于脱髓鞘斑块累及神经轴的广泛性。最近，我们在这组患者中遇到了一个特定的亚组，他们有特征性的临床主诉，如排尿犹豫、用力和排尿不完全、检查时会阴感觉减退、膀胱测压和结肠测压时无反射以及电生理参数提示圆锥马尾受累。本文报告了2例患者，详细阐述并讨论了这种迄今为止在多发性硬化症中假定但未被证实的神经内脏功能障碍机制。
