Chandra R S, Altman R P
J Pediatr. 1978 Aug;93(2):196-200. doi: 10.1016/s0022-3476(78)80495-8.
Atretic ducts were studied in 34 infants undergoing the portoenterostomy procedure for biliary atresia. The specimens were grouped into three categories on the basis of the size of the lumen at the proximal margin: Type I with a lumen 150 mu or greater, Type II with single to multiple ductal structures measuring less than 150 mu, and Type III with no identifiable epithelium-lined structures in fibrous connective tissue. A significant correlation existed between postoperative bile drainage and the duct type; bile drainage occurred in all five patients with Type I ducts, 18 of 21 patients with Type II ducts, and one of eight patients with Type III ducts. Furthermore, the duct type was the only feature that correlated with the ultimate outcome. Ductal inflammation and hepatic histology did not correlate with postoperative bile drainage or clinical course.
对34例因胆道闭锁接受肝门空肠吻合术的婴儿的闭锁胆管进行了研究。根据近端边缘管腔大小，将标本分为三类：I型管腔为150μm或更大；II型为单个至多个直径小于150μm的导管结构；III型在纤维结缔组织中无明显的上皮内衬结构。术后胆汁引流与胆管类型之间存在显著相关性；I型胆管的所有5例患者均出现胆汁引流，II型胆管的21例患者中有18例出现胆汁引流，III型胆管的8例患者中有1例出现胆汁引流。此外，胆管类型是与最终结局相关的唯一特征。胆管炎症和肝脏组织学与术后胆汁引流或临床病程无关。
